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Herplex - Idoxuridine

Idoxuridine (Herplex) is a water-soluble iodinated derivative of deoxyuridine that inhibits several DNA viruses including HSV, VZV, vaccinia, and polyoma virus. The triphosphorylated metabolite of idoxuridine inhibits both viral and cellular DNA synthesis and is also incorporated into DNA. Such modified DNA is susceptible to strand breakage and causes aberrant viral protein synthesis. Because of its significant host cytotoxicity, idoxuridine cannot be used to treat systemic viral infections The development of resistance to this drug is common. [Pg.574]

Intraocular implant (Vitrasert) 4.5 mg ganciclovir/implant Idoxuridine (Herplex)... [Pg.1089]

Idoxuridine Dendrid , Herpid , Herplex , Kerecid , Stoxil ... [Pg.374]

SYNS ALLERGAN 211 DENDRID l-(2-DEOXY-P-d-RIBOFURANOSYL)-5-IODOURACIL l-P-d-2 -DEOXYRIBOFURANOSYL-5-IODOURACIL EMANIL HERPESIL HERPIDU HERPLEX HERPLEX LIQUIFILM IDEXUR IDOXENE IDOXURIDIN IDOXURIDINE IDU IDUCHER IDULEA IDUOCULOS IDUR IDURIDIN 5-IODODE-OXYURIDINE 5-IODO-2 -DEOXYURIDINE 5-lODOURACIL DEOXYRIBOSIDE lUDR 5-IUDR JODDEOXIURIDIN KERECID NSC-39661 OPHTHALMADINE SKStF 14287 STOXIL SYNMIOL... [Pg.425]


See other pages where Herplex - Idoxuridine is mentioned: [Pg.1705]    [Pg.358]    [Pg.359]    [Pg.1705]    [Pg.1705]    [Pg.1705]    [Pg.358]    [Pg.359]    [Pg.1705]    [Pg.1705]    [Pg.623]    [Pg.31]    [Pg.554]    [Pg.1154]    [Pg.150]    [Pg.321]    [Pg.338]    [Pg.333]    [Pg.623]   


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Idoxuridine

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