Thiolcarbamate herbicide

Fig. 22.12 Profile optimization using PLS for fungicidal and herbicidal thiolcarbamates.

Miyashita, Y., Ohsako, H., Takayama, C. and Sasaki, S. (1992) Multivariate structure-activity relationships analysis of fungicidal and herbicidal thiolcarbamates using partial least squares method. Quant. Struct.-Act. Relat. 11 17-22. 

Smith, A.E. and Fitzpatrick, A. The loss of five thiolcarbamate herbicides in nonsterile soils and their stability in acidic and... 

F Cubero, J Rodriguez, L Hernandez. Determination of thiolcarbamate herbicides in natural water by HPLC with spectrometric detection. Fresenius J Anal Chem 343 382-385, 1992. 

Molinate. The thiolcarbamate molinate also appeared to be a good target for ELISA but for different reasons than existed for paraquat. The herbicide is used extensively on rice in the Sacramento Valley and each year is detected as a contaminant in drainwaters from the field and in the Sacramento River. There are many water samples taken each year for molinate analysis and some other chemicals used for pest control on rice. Thus, an ELISA could be put to immediate use supplementing or perhaps replacing entirely the conventional method based upon extraction of water, followed by GC analysis of the extract. 

Figures 9 and 10 describe a similar pesticide example based.on the Stauffer Chemical series of thiolcarbamate herbicides. The implied optimum in transport or binding is...

Although thiolcarbamates are a well known class of herbicides (9 ), little Is known regarding their juvenold... 

Fig. 22.13 PLS projections of thiolcarbamates data of the first latent variable fi against the second latent variable t2- The size of the circles denote the fungicidal (F) or herbicidal (H) activity.

Smith, A.E. and A. Fitzpatrick. The Loss of Five Thiolcarbamate Herbicides in Nonsterile Soils and Their Stability in Acidic and Basic Solutions, J. Agric. Eood Chem., 18(4) 720-722 (1970). 

Tilles and Antognlnl were awarded five patents (43-47) covering the synthesis and use as herbicides for the above titled commercial thiolcarbamates. In addition, Tilles (48) published an excellent paper covering the synthesis of 250 thiolcarbamates. 

The discovery that crop tolerance for a particular herbicide could be enhanced has led to the identification of many compounds that antidote the herbicidal effect of the thiolcarbamate herbicides. iV,A/ -Diallyl-dichloroacetamide was the first material commercialized with thiocarbamate herbicides for use in corn. This same concept also has application for other types of herbicides. Also it was discovered that repeated application of the same thiolcarbamate led to rapid microbial degradation of the material in the soil. Addition of extenders to the thiolcarbamate herbicide counteracted with degrading effect of the microorganisms in the treated soil. 

A number of substituted thiirans have been obtained by displacement of chlorine from chloromethylthiiran. Aryloxymethylthiirans have been used for the synthesis of antidepressant thiomorpholine derivatives, and thiolcarbamates derived from 2-mercaptomethylthiiran are claimed to be herbicides. A dimethylthiiran substituted with a long carbon chain containing a dienoate group is said to be insecticidal. ... 

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