Herbicidal activity, screening library

Figure 9.28 Synthesis of the primary SP amide/ester library L17 tested for herbicidal activity and structure of the hit 9.69 derived from its screening.

The library was prepared using automated liquid handling methods and active confounds were discovered in all three disciplines herbicide, fungicide and insecticide. One of the library numbers, conq)ound 14 depicted in Figure 9, was advanced to lead status based on its excellent preventative, curative and residual activity against wheat powdery mildew seen in our fungicide screens. 

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