Rutae herba

Paulini, H., U. EUert, and O. Schimmer. 1987. Mutagenic com-poimds in an extract from rutae herba (Ruta graveolens L.). I. Mutagenicity is partially caused by furoquinoline alkaloids. Mutagenesis 2(4) 271-273. 

Schimmer, O., and I. Kuhne. 1990. Mutagenic compounds in an extract from rutae herba Ruta graveolens L.). II. UV-Amediated mutagenicity in the green alga Chlamydomonas reinhardtii by furoquinoline alkaloids and furocoumarins present in a commercial tincture from rutae herba. Mutat. Res. 243(l) 57-62. 

Rutae herba can be characterized by its coumarins (e.g. rutamarin), the furano-coumarins (e.g. bergapten, psoralen) as well as the furanoquinoline alkaloids (e.g, kokusagine, Y-fagarine) and the flavonol glycoside rutin. 

Rutae herba (1) generates with KOH reagent in solvent system I a band of ten to 12 violet and blue fluorescent zones from R, 0.2 up to the solvent front, Rutarin (Tl) forms a major white-blue fluorescent zone at R,. 0.35. 

Separation of Rutae herba (1) extract in solvent system II yields more than ten blue fluorescent zones from the start up to Rf — 0.9. Red zones are chlorophyll compounds. 

NovAk, I., Z. Rozsa, Y. W. Mirrhom, K. Szenorh, J. Reisch, and E. Minker Isolation of Active Substances from Ruta Roots III. Marmesin, Marmesinin, Rutacultin and a Rutamarin Alcohol. Herba Hung. 11, 13 (1972) Chem. Abs. 79, 102812 (1973). 

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