Heparin, bleeding risk

Use heparin lock-flush solution with caution in infants with disease states in which there is an increased danger of hemorrhage. The use of the 100 unit/mL concentration is not advised because of bleeding risk, especially in low-birth-weight infants. 

When HD is not required immediately after insertion (desirable to avoid bleeding risk associated with heparin administration), the patient should re-... 

Heparin may be given along with and/or after administration with a thrombolytic drug to prevent another thrombus from forming. However, administration of an anticoagulant increases the risk for bleeding. The patient must be monitored closely for internal and external bleeding. 

There is an increased risk for bleeding when the patient receiving heparin is also taking. ... 

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