Henry reactions, copper® acetate

The enantioselective Henry reaction by using copper acetate-bis(oxazoline) catalyst is reported by Evans . ... 

A syn- and enantio-selective Henry reaction employs copper(II) acetate and a chiral -amino alcohol catalyst. 

Vinylation Studies in the Absence of Copper(II). Our results obtained with various systems in the absence of cupric salts—i.c., a one-pass reaction of palladium (II), are given in Table I. No higher boiling products were obtained than hexenyl acetates. This agrees with Henry (20), who reports that in this system (Pd (II), HOAc, NaOAc) cupric ion is necessary for forming higher boiling products. 

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