Heme proteins reactions with hydrogen peroxid

Lignin (LiP) and manganese dependent (MnP) peroxidases of R chrysosporium are secreted in conjunction with a number of other enzymes and chemicals under nutrient deficient conditions (3, 33, 44-47, 86, 92, 93). The peroxidases are known to catalyze a number of free radical reactions. Research on these enzymes has been extensively reviewed recently (5, 49, 85). The resting enzyme (ferric-heme protein) is initially oxidized by two electrons in a reaction with hydrogen peroxide (Fig. 6). The resulting intermediate, com-... 

Reactions of hydrogen peroxide with proteins are generally slower than those with superoxide anion. H2O2 reacts with heme proteins, producing theFe(IV)-oxo... 

Several heme-containing proteins, including most peroxidases 12), have been observed to exhibit a low level of catalatic activity, with the chloroperoxidase from Caldariomyces fumago exhibiting the greatest reactivity as a catalase (13-15). Despite the fact that there is as yet only one such example to consider, it provides an alternate mechanism for the catalatic reaction and is addressed in this review. It was first characterized for its ability to chlorinate organic substrates in the presence of chloride and hydrogen peroxide at acid pH, but was later found... 

Reactions of Heme Proteins with Oxygen or Hydrogen Peroxide... 

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