Heme oxygenase bacteria

Zhu W, A Wilks, I Stojiljkovic (2000) Degradation of heme in Gram-negative bacteria the product of the hemO gene of Neisseriae is a heme oxygenase. J Bacterial 182 6783-6790. 

The second heme oxygenase (HO-2) is distributed widely among tissues, but it is most abundant in certain neurons in the brain.437 4373 Its major function may be to generate CO, which is now recognized as a probable neurohormone (Chapter 30). Bacteria, such as Corynebacterium diphtheriae, employ their own heme oxygenase as a means of recovering iron that they need for growth.438... 

Paramagnetic centers are found in many specific enzymes and proteins that function in animal tissues and bacteria (oxygenases, sulfite or nitrite reductases, xanthine oxidase, nitrogenase, etc.) besides mitochondria and microsomes. The catalytic site can include Mo, Cu, Co, Ni, Mn, and other metal ions. Elowever heme- and iron-sulfur centers constitute the majority of the paramagnetic centers found outside the mitochondria. 

---