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Helenalin

Tornhamre S, Schmidt TJ, Nasman-Glaser B, Ericsson I, Ake L. Inhibitory effects of helenalin and related compounds on 5-lipoxygenase and leukotriene C4 synthase in human blood cells. Biochem Pharmacol 2001 62 903-911. [Pg.65]

N.A. Inula helenium L. Inulin, resin, mucilage, helenalin, dammaranedienol." For asthma, chest cold, stomach ulcers, antitussive, diuretic, antiseptic. [Pg.273]

Michael addition of glutathione to the sesquiterpene lactones dehydrocostuslactone and helenalin. [Pg.151]

Schmidt, T. J. 1997. Helenanolide-type sesquiterpene lactones-l 11. Rates and stereochemistry in the reaction of helenalin and related helenanolides with sulfhydryl containing biomolecules. Bioorg. Med. Chem. 5, 645-653... [Pg.159]

Sql22 Helenalin isobutyrate A. montana NFAT, NFkB... [Pg.90]

Drugs to combat cancer act on a range of biochemical pathways, but most commonly on processes that cancerous cells need to use to proliferate rapidly, one class attacks DNA polymerase, an enzyme needed to make the copy of DNA that has to be provided for each new cell. Helenalin and vernolepin are two such drugs, and if you look closely at their structure you should be able to spot two ot,p-unsaturated carbonyl groups in... [Pg.238]

Helenalin Anaphalis, Arnica, Balduina, IKK-NFkB complex... [Pg.319]

Helenalin Anaphalis, Balduina, Gaillardia, Apoptotic (AROM)... [Pg.393]

Allergenic effects. A number of secondary metabolites influence the immune system of animals, such as coumarins, furanocoumarins, hypericin, and helenalin. Common to these compounds is a strong allergenic effect on those parts of the skin or mucosa that have come into contact with the compounds (4,17,312). Activation or repression of the immune response is certainly a target that was selected during evolution as an antiherbivore strategy. The function of alkaloids in this context is hardly known. [Pg.60]


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Helenaline

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