Heart-lung transplantation following

Carrier M, White M, Perrault LP, et al. A 10-year experience with intravenous Thymoglobuline in induction of itmntmosuppression following heart transplantation. J Heart Lung Transplant 1999 18 1218-1223. 

Two of the patients with a response to nitric oxide gas that precluded transplantation of the heart alone died one, following combined heart lung transplantation, and one, of an intercurrent pneumonia while awaiting suitable donor organs. The pulmonary histology confirmed severe and irreversible pulmonary vascular changes in both patients. 

Shiba N, Chan MCY, Kwok BW, Valantine HA, Robbins RC, Hunt SA (2004) Analysis of survivors more than 10 years after heart transplantation in the cyclosporine era Stanford experience. J Heart Lung Transplant 23(2) 155-164 Shirazi KK, Amendola MA, Tisnado J et al (1983) Radio-graphic findings in the chest of patients following cardiac transplantation. Cardiovasc Intervent 6 1-6 St Goar FG, Pinto FJ, Alderman EL et al (1992) Intracoronary ultrasound in cardiac transplant recipients in vivo evidence of angiographically silent intimal thickening. Circulation 85 979-987... 

Currently, since the safety and efficacy of SRL has not been established in liver or lung transplants, it is recommended that its use be avoided in these populations immediately following transplant. In contrast, limited data on the use of SRL in heart transplantation indicate benefit in reversing acute rejection in patients who do not respond to antilymphocyte therapy. Furthermore, SRL may slow the progression of vasculopathy, which may have an impact on chronic rejection and long-term patient survival after heart transplantation. ... 

Griffith BP, Hardesty RL, Trento A, Bahnson HT. 1985. Asynchronous rejection of heart and lungs following cardiopulmonary transplantation. Ann Thorac Surg. 40 488-493. 

Clinical Use. Cyclosporine (Neoral, Sandimmune) is one of the primary medications used to suppress immune function following organ transplantation.14 21 69 This medication can be used alone or combined with glucocorticoids, azathioprine, and other immunosuppressants to prevent the rejection of a kidney, lung, liver, heart, pancreas, and other organ transplants. 

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