Hartman

A new synthesis of 4-cyanothiazole derivatives via a-metailated isocyanides and thionoesters have been reported by Hartman and Wein-stock (Scheme 144) (812), with R2 = H, Me, n-C3H7, Ph, PhCHj. 4-Cyanothiazole (in 50% yield) was also formed by condensing thio-fonnamide with Q2C=C(NH2)CN (803). 

F. X. Hartman, Solid Propellants Safety Handbook, Spriagfield, Va., 1965. 

R. E. Sekeika in P. Hartman, ed., Cysta/Growth An Introduction Noith-HoUand Publishing Co., Amsterdam, the Netherlands, 1973, Chapt. 15. 

Isolation of the mills, use of nonsparldng materials of construction, and magnetic separators to remove foreign magnetic material from the feed are useful precautions (Hartman, Nagy, and Brown, U.S. Bur. Mines Rep. Invest. 3722, 1943). Stainless steel has less sparking tendency than ordinary steel or forgings. 

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