Haloperidol benztropine

D6 Tricyclic antidepressants (TCAs), benztropine, perphenazine, clozapine, haloperidol, codeine/oxycodone, risperidone, class Ic antiarrhythmics, 3 blockers, trazodone, paroxetine, maprotiline, amoxapine, duloxetine, mirtazapine (partly), venlafaxine, bupropion Fluoxetine, paroxetine, duloxetine, hydroxybupropion, methadone, cimetidine, haloperidol, quinidine, ritonavir Phenobarbital, rifampin... 

Sheikh RA, Prindiville T, Yasmeen S. Haloperidol and benztropine interaction presenting as acute intestinal pseudo-obstruction. Am J Gastroenterol 2001 96(3) 934-5. 

Benztropine Seven patients developed delirium when given fluoxetine, paroxetine, or sertraline with benztropine in the presence of perphenazine or haloperidol. Other patients remained symptom-free. 

Extracted acetophenazine, benztropine, butaperazine, carphenazine, chlorpromazine, flu-phenazine, haloperidol, imipramine, mesoridazine, nortriptyline, orphenadrine, pipera-cetazine, promazine, promethazine, thioridazine, thiothixene, trifluoperazine, trifluprom-azine, trihexyphenidyl, trimeprazine... 

Extracted amitriptyline, benztropine, brompheniramine, chlorpheniramine, chlorproma-zine, clomipramine, ( roheptadine, desipramine, diphenhydramine, dothiepin, doxepin, haloperidol, imipramine, loxapine, maprotiline, meperidine, mesoridazine, methadone, metoclopramide, mianserin, moclobemide, nomifensine, nordoxepin, norfluoxetine, nor-propo q)hene, northiaden, nortriptyline, pentoharhital, pheniramine, promethazine, propoxyphene, propranolol, protriptyline, quinidine, quinine, sulforidazine, thioridazine, thiothixene, tranylcypromine, treizodone, trihe q)henidyl, trimipramine, triprolidine Noninterfering dextromethorphan, norphetidine, phenoxyhenzamine, prochlorperazine, trifluoperazine Interfering amoxapine... 

Discontinue haloperidol and observe the patient Give oral diphenhydramine Switch the patient to fluphenazine Inject benztropine... 

SheildiRA,PrindivilleT, YasmeenS. Haloperidol and benztropine interaction presentii as acute intestinal pseudo-obstractioa AmJ Gastroenterol (2001) 96,934-5. 

Singh, M. M. and Kay, S. R. (1975) A comparative study of haloperidol and chloipromazine in terms of clinical effects and therapeutic reversal with benztropine in schizophrenia. Theoretical implications for potency differences among neuroleptics. Psychopharmacologia (Berl), 43, 103. 

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