Macrolides, halogenated

Buchanan GO, Williams PG, Feling RH, Kauffman CA, Jensen PR, Fenical W (2005) Sporolides A and B Structurally Unprecedented Halogenated Macrolides from the Marine Actinomycete Salinispora tropica. Org Lett 7 2731... 

Buchanan, G,0 Williams, P,G Feling, R.H., Kauffman, C.A, Jensen, P.R., and Fenical, W, (2005) Sporolides A and B Structurally unprecedented halogenated macrolides from the marine actinomycete Salinispora tropica. Org. Lett., 7, 2731-2734. 

Matthew, S., Salvador, L.A., Schupp, P.J., Paul, V.J., and Luesch, H. (2010a) Cytotoxic halogenated macrolides and modified peptides from the apratoxin-producing marine cyanobacterium Lyngbya bouillonii from Guam./. Nat. Prod., 73,1544-1552. 

Strobel and co-workers isolated haterumalide NA/oocydin A (2) from bacteria Sermtia marcescens [10]. Haterumalide NA was also obtained from a soil bacterium [11]. The isolation of similar compounds from two unrelated invertebrates such as the ascidian Lissoclinum sp. and the sponge of Ircinia sp., and the microorganisms, supports the potential microbial origin of haterumalides [12-15]. Although more than 200 marine macrolides have been recorded since the first isolation of the aplysiatoxins, halogenated marine macrolides are rarely found [16, 17]. 

Ceodia, Sidonops Macrolides, cyclopeptides, halogenated cyclic depsipeptides, original purines and nucleosides... 

Data in the literature show that the secondary metabolites of hadromerid sponges show few significant differences from those of the Astrophorida. There are a few halogenated or sulfated molecules, peptides, depsipepti-des and especially macrolactones (macrolides) in the genera Latrunculia and Spirastrella. These have led to the discovery of an important family of antitumor substances. 

Smenospongia, Fasciospongia 50 40 Terpenes, macrolides, halogenated aromatic derivatives... 

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