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Haliclona valliculata

In the extract of fungus Emericella variecolor, derived from the marine sponge Haliclona valliculata, two new natural products, evariquinone 41 and isoemericellin 42, were isolated. Compound 41, which also can be obtained from terrestrial fungus, showed anti-proliferative activity towards KB (60% inhibition) and NCI-H460 cells (69% inhibition) at a concentration of 3.16 mg mL... [Pg.207]

Taken from the sponge Haliclona valliculata harvested on the Island of Elba, at a depth of 20-30 m, the fungus Emericella variecolor produces in culture several anthraqui-none derivatives including evariquinone, an original molecule which is antiproliferative for KB cells, with an IC50 of 3.16[xgml (Bringmann et al, 2003). [Pg.542]


See also in sourсe #XX -- [ Pg.207 ]




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