Halichondria japonica

Hayashi A, Nishimura Y, Matsubara T. Occurrence of ceramide digalactoside as the main glycosphingolipid in the marine sponge Halichondria japonica. Biochim. Biophys. Acta 1991 1083 179-186. 

New ceramide digalactosides were isolated by Hayashi s group from the marine sponge Halichondria japonica.24 To the major glycosphingolipid was assigned the structure 86, except for the stereochemistry, using FAB/MS, IR and NMR spectroscopy. The first synthesis of the ceramide 87 and therefore the structure determination were described by us.25... 

Yamaoka Y Caemona ml, Oclarit JM, Jin K and Shibata Y (2001) Arsenic compounds in marine sponge (Haliclona permolis, Halichondria japonica, Halichondria okaidai and Haliclona sp. white) from Seto Inland Sea, Japan. Appl Organomet Chem 15 261-265. 

Three new chlorinated derivatives of tyrosine [gymnastatins A (12), B (13) and C (14)] were isolated as colorless powders from the mycelium of a strain of Gymnascella dankaliensis (Gymnoascaceae) from a Japanese sponge Halichondria japonica. Their stereostructure was established on the basis of spectral analysis [68]. 

Gymnastatins. Cytotoxic spirocyclic compounds produced by a strain of Gymnascella dankaliensis, which was isolated from the sponge Halichondria japonica, e.g., G. B C24HJ5CI2NO5, Mr 488.44, powder, [ajp -122° (CHClj). 

Bacillus cereus (QN03323) Sponge (Halichondria japonica) Cyclic thiopeptides (YM-266183, YM-266184) Antibiotics Nagai etaf., 2003 Suzumara et a/., 2003a, 2003b... 

Water-soluble arseno-compounds were detected in freeze-dried samples of the marine sponges Halichondria permolis (13 pg/g dry wt), H. japonica (3.42 pg/g dry wt), H. okadai (5.5 pg/g dry wt) and Flaliclona sp. (0.81 pg/g dry wt), which were collected near Japan. Arsenobetaine 54... 

In the sesquiterpenoid moiety the paniceins have the uncommon feature of an aromatic ring which, notably, has been encountered already in renieratene (126) and isorenieratene (127). These are arylcarotenoids found in the sponge Reniera japonica (syn. Halichondria panicea) 183, 184), which also yielded a third aromatic carotenoid renierapurpurin (130) 185). 

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