H-transfers Coupled to Major Heavy Atom Motions

H-transfers Coupled to Major Heavy Atom Motions 

In many H-transfer reactions in solution the reaction centers have first to form a reactive complex from non-reactive configurations or conformations i.e. they require a major molecular mobility. Therefore, it is understandable that complex H-transfers cannot take place in the solid state. In this section, various experimental published cases will be discussed. 

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Therefore, in the first part of this section, intramolecular hydrogen transfers or intermolecular hydrogen transfers in preformed hydrogen bonded complexes in the solid state which are coupled only to minor heavy atom motions are discussed. H-transfers coupled to major heavy atom motions will then be treated in the second part they include pre-equilibria, hydrogen bond switches, conformational changes, solvent motions etc. 

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