Guanine hydrochloride, structure

In guanine hydrochloride dihydrate [GUANCD] (Fig. 15.22), the hydrogen-bond structure is a three-dimensional net. The positive charge appears to be located on N(7). The Cl" is four-coordinated, and five-coordinated when the minor component from the N(2) amino group is included. One water molecule is three-coordinated, the other four-coordinated. 

Fig. 13. drawing of the crystal structure of guanine hydrochloride monohydrate. Hydrogen bonds are indicated by dashed lines. 

After inconclusive early work,-" structure 218 was demonstrated for adenine hydrochloride using X-ray diffraction (cf. also reference 256) and was later supported by nuclear magnetic resonance evidence. Four possible structures have been advanced for guanine... 

Traube. ibid. 33, 1371 (1900) Ger. pats. 134,984 (1903), 158,591 (1903). 162,336 (1904). Prepn of, 5N-isotopic guanine following Traube s synthesis Plentl, Schoenheimer, J. Biot. Chem. 153. 203 (1944). Several desmotropic forms. Crystal structure of hydrochloride monohydrate Broom -... 

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