Guaiacol 4-nitro

Eupe also found that one osmophore can be replaced by another without greatly altering the type of the odour, thus vanilline, p-nitro-guaiacol, and p-cyanoguaiacol all have similar odours but varying in strength. 

A spectrophotometric determination of parathion-methyl (258) in soil and various vegetables is based on reduction of the nitro group to an amino group with zinc/HCl, dia-zotization and coupling with guaiacol (259) to form a yellow-colored azo dye in alkaline medium532. 

Nitro guaiacol, yel ndls (subl), mp 62° sol in w, steam distils. Prepd by nitration of guaiacol in HAc at RT... 

Guaiacol, bromoxynil, ioxynil, trichlorosyringol, o-chloiovanillin, dinoseb, and 11 chloro-, nitro- and methyl-substituted phenols were baseline resolved on a Cjg column using a 24-min 33/64 — 75/25 (90/10 acetonitrile/methanol with 0.015% TFA)/water (0.05% TFA) gradient. The monitored wavelength was changed from 280 to 230 nm at 7.8 min. Peak shapes woe uniformly excellent. Detection limits were <20 ng injected for each analyte. With a preextraction process described in the paper, overall detection limits were reported as 0.1 pg/L [932],... 

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