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GTPase-activating center

The L2 loop is of particular importance for the biological activity of the Ras protein. L2 contains the amino acids 32-36, which were recognized in mutation experiments as important for the interaction with GTPase-activating proteins. Thr35 of the L2 loop also participates in H-bridge contacts to the y-phosphate and to Mg +, and thus helps to correctly position the GTP-Mg complex in the active center. [Pg.329]

See other pages where GTPase-activating center is mentioned: [Pg.363]    [Pg.363]    [Pg.364]    [Pg.364]    [Pg.371]    [Pg.372]    [Pg.373]    [Pg.375]    [Pg.1668]    [Pg.1672]    [Pg.1684]    [Pg.1687]    [Pg.1691]    [Pg.755]    [Pg.759]    [Pg.774]    [Pg.778]    [Pg.734]    [Pg.738]    [Pg.753]    [Pg.363]    [Pg.363]    [Pg.364]    [Pg.364]    [Pg.371]    [Pg.372]    [Pg.373]    [Pg.375]    [Pg.1668]    [Pg.1672]    [Pg.1684]    [Pg.1687]    [Pg.1691]    [Pg.755]    [Pg.759]    [Pg.774]    [Pg.778]    [Pg.734]    [Pg.738]    [Pg.753]    [Pg.361]    [Pg.364]    [Pg.365]    [Pg.365]    [Pg.201]    [Pg.333]    [Pg.263]    [Pg.102]    [Pg.444]    [Pg.147]    [Pg.212]    [Pg.88]    [Pg.7]    [Pg.406]    [Pg.481]    [Pg.291]    [Pg.265]    [Pg.241]    [Pg.170]    [Pg.211]    [Pg.190]    [Pg.52]    [Pg.395]    [Pg.366]    [Pg.31]   
See also in sourсe #XX -- [ Pg.1687 ]



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Active centers

Active centers activity

GTPase

GTPase activity

GTPase center

GTPase-activating center of ribosomes

GTPases

Ribosome GTPase activating center

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