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Growth regulators, resistance induction

The interferons are naturally protective substances. Type I IFNs are produced by most cells in response to viruses, bacteria or their products. For example, IFN-a and IFN- (3 are produced in response to viral infection and inhibit viral replication plus assist the induction of viral resistance. Not only do they possess antiviral activity but they also mediate the response to other infectious agents, demonstrate antitumor activity, and play a role in the regulation of growth, differentiation and development [211]. In contrast, IFN-y has more potent immunoregulatoiy effects than either IFN-a or -(3. Among its properties, IFN-y is capable of activating human macrophage oxidative metabolism and microbicidal activity. [Pg.110]

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See also in sourсe #XX -- [ Pg.155 , Pg.156 ]



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