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GroES capping

Figure 7.41. Schematic representation of the chapt-eronin refolding machine composed of a twofold GroEL (body)/GroES (cap). Misfolded protein unfolds in polar cavity due to seven ATPs and properly refolds as seven Pi are released stepwise. Figure 7.41. Schematic representation of the chapt-eronin refolding machine composed of a twofold GroEL (body)/GroES (cap). Misfolded protein unfolds in polar cavity due to seven ATPs and properly refolds as seven Pi are released stepwise.
Estimate of Change in AG ha of Inner Wall on Nucleotide Binding and GroES Capping... [Pg.314]

Of course, a visualization of this GroEL/ GroES Anfinsen cage is incomplete without a representation of the GroES cap of the cage. [Pg.317]

A.2 Effect of ATP Binding and GroES Capping on the Substrate s Movable Cusp of Insolubility... [Pg.318]

Figure 7.48. Stereo view of the aqueous chamber side of the GroES cap at the GroEL-GroES junction for the asymmetric (ADP)7-GroEL structure. The purpose is to estimate surface polarity by obtaining a sum over AGha for the face and to compare the value to the inner faces of GroEL as... Figure 7.48. Stereo view of the aqueous chamber side of the GroES cap at the GroEL-GroES junction for the asymmetric (ADP)7-GroEL structure. The purpose is to estimate surface polarity by obtaining a sum over AGha for the face and to compare the value to the inner faces of GroEL as...
Seven GroES, 10,000 Da protein molecules, bind coincident with ATP binding at one end of the D7 GroEL structure to cap the structure and enclose a water-filled cavity of 175,000 A with the capacity to contain protein or peptide substrate inside of a size up to 70kDa. [Pg.305]

The co-chaperonin GroES, containing seven subunits [106], caps the GroEL particle as a dome. A remarkable feature, which has mechanistic implications, is... [Pg.62]


See other pages where GroES capping is mentioned: [Pg.519]    [Pg.519]    [Pg.307]    [Pg.307]    [Pg.311]    [Pg.314]    [Pg.318]    [Pg.319]    [Pg.519]    [Pg.519]    [Pg.307]    [Pg.307]    [Pg.311]    [Pg.314]    [Pg.318]    [Pg.319]    [Pg.8]    [Pg.329]    [Pg.152]    [Pg.324]    [Pg.518]    [Pg.324]    [Pg.518]    [Pg.519]    [Pg.41]    [Pg.48]    [Pg.48]    [Pg.51]    [Pg.81]    [Pg.70]    [Pg.152]    [Pg.1617]    [Pg.294]    [Pg.495]    [Pg.305]    [Pg.308]    [Pg.310]    [Pg.310]   
See also in sourсe #XX -- [ Pg.315 , Pg.318 ]




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