Grignard and Alkali-Metal Reagents

Most of the tetradentate tripod-like ligands of the type A—C 

CH3C(CH2C1)3 + 3NaP/ 2 - CH3C(CH2P/ 2)3 + 3NaCl R = Ph, Et 

Although there are limitations with synthetic routes that use the classical Grignard and organolithium reagents, these methods are still widely used. Some recent applications to somewhat unusual ligands are illustrated below. Capka et treated a series of alkoxylsilyl- 

The interesting tripod molecule MeSi(PBu2)3 was prepared in 70% yield by treating MeSiCls with LiPBu2 in diethyl ether at -80 C. 

Syntheses of derivatives of tris(diphenylphosphino)methane have been 

---