Great Yang

The essence of Great Yang obtains its power from the sun. 

Numerical values for solid diffusivities D,j in adsorbents are sparse and disperse. Moreover, they may be strongly dependent on the adsorbed phase concentration of solute. Hence, locally conducted experiments and interpretation must be used to a great extent. Summaries of available data for surface diffusivities in activated carbon and other adsorbent materials and for micropore diffusivities in zeolites are given in Ruthven, Yang, Suzuki, and Karger and Ruthven (gen. refs.). 

It was with great pleasure that I read the first book of Yifan Yang in 2002. This was Chinese Herbal Medicines Comparisons and Characteristics. What was so refreshing about Comparisons and Characteristics was the clear and detailed description of the functions of the different temperature and taste properties, so that the reader understood why different herbs have different actions. The author then developed this into the excellent contrasts of similar herbs based on differences in temperature, taste, and action. This is vital to the clinical practice of herbal medicine. If the practitioner does not understand the detailed differences between herbs, then they cannot make effective herb combinations. 

The modulation of the N-type Ca2+ channels has been shown for some presynaptic receptors to be the mechanistic basis for the inhibition of Ca2+ influx [29]. In 1989 Takemura et al. [30] reported on the effective inhibition of histamine release from rat hypothalamic slices by the N-type Ca2+ -channel blocker ca-conotoxin. In addition Endou et al. [23] showed that to-conotoxin greatly potentiated the modulatory effect of (R)a-methylhistamine on cardiac adrenergic responses. Yang and Hatton [31] provided direct evidence for an H3 receptor-mediated modulation of ion permeability of neurons. They showed that in magnocellular histaminergic neurons from the rat posterior hypothalamus, H3... 

The /8 subunit of tryptophan synthase from E. coli is inactivated by a mutation at Gly-281 (G281R).108 Gly-281 is located at a sharp turn in the trypsin-sensitive, subdomain (residues 260-310) that makes several contacts with the a subunit.7) The G281R mutation alters the catalytic properties of the isolated /8 subunit and weakens association with the a subunit. The mutation may interfere with hydrophobic interactions between the N-terminal and C-terminal domains of the /8 subunit and prevent a conformational change that affects catalytic properties and subunit interaction.108 Insertion of arginine or tryptophan between tyrosine 279 and phenylalanine 280 of the /3 subunit greatly weakens subunit interaction and decreases catalytic activity (X.-J. Yang and E.W. Miles, unpublished results). 

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