Gram-positive fungi

Neosidomycin (63) and SF-2140 (64) are indole N-glycosides produced by S. hjgroscopicus A.ctinomadura respectively (195,196). A revised stmcture for (63) has appeared (197). Compound (64) contains an a-N-glycoside linkage. Both (63) and (64) show activity against gram-positive bacteria, yeast, fungi, and vimses. 

Activity against gram-positive bacteria = P gram-negative bacteria = N mycobacteria = M fungi = F tumors = T and viruses = V. Only peptides not discussed in the text of this article are given references. 

Actinomycete Nontaxonomic term applied to a group of high G -1- C base composition. Gram-positive bacteria that have a superficial resemblance to fungi. Includes many but not all organisms belonging to the order Actinomycetales. 

The sites of infections that most frequently led to sepsis were the respiratory tract (21% to 68%), urinary tract (14% to 18%), and intraabdominal space (14% to 22%). Sepsis may be caused by gram-negative (38% of sepsis) or gram-positive bacteria (40%), as well as by fungi (17%) or other microorganisms. 

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