Gradient development graphical method

Matano developed a graphical method which, for certain classes of boundary value problems, relates the form of the diffusion profile with the concentration dependence of the interdiffusivity, D(c), introduced in Section 3.1.3 [5]. This method can determine D(c) from the diffusion profile in chemical concentration-gradient diffusion experiments where atomic volumes are sufficiently constant so that changes in overall specimen volume are insignificant and diffusion can be formulated in a F-frame. The method uses scaling, as discussed in Section 4.2.2. 

Hofstee plot A graphical method used in enzyme kinetics to obtain a straight line fiom experimental data. It involves forming aplotofV/SversusVinwhichSis the substrate concentration at which the velocity v is observed. The gradient of the line is equal to -K and the intercept on the y-axis is equal to the maximum velocity V. Also known as the Eadie-Hofstee plot, it is named after Canadian biochemist George Sharp Eadie (1895-1976) and B. H. J. Hofstee who developed the plot in 1942 and 1959, respectively. See michaelis-MENTEN KINETICS. 

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