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GPCRs receptors

Atrial natriuretic peptide binds to the GPCR receptor. [Pg.86]

The 5-HT6 receptor was first cloned by sequence homology with another GPCR receptor, the histamine H2 receptor, from a rat brain cDNA library (206) and by PCR from a rat striatal cDNA library (207). Later, the human (208) and the mouse (209) 5-HT6 receptors were also cloned. This receptor... [Pg.343]

Strategies for Ligand identification for Orphan GPCR Receptors... [Pg.3120]

Simultaneous modulation of several signaling systems GPCR receptor mosaics for the decoding of drug signals... [Pg.70]

The Oj receptors (and and receptors (and are GPCRs. receptors couple to a variety of effectors (Table 6-6), generally inhibiting adenylyl cyclase and activating G protein-gated channels, resulting in membrane hyperpolarization (possibly via Ca -dependent processes or from direct interaction of liberated /3y subunits with channels). [Pg.111]


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GPCRs

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