Goitrogenesis in iodine deficiency

The original assumption about goitrogenesis in iodine deficiency was that the lack of iodine decreased thyroid hormone production, thereby causing an increase in TSH, which would stimulate thyroid growth. Hhile many subjects in iodine deficiency areas do not have abnormally elevated TSH levels, their,mean serum TSH concentration is higher that that in a non iodine deficient control population. This difference is especially... 

---