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Glycosyltransferases in Glycosphingolipid Biosynthesis

Figure 5 Pathways of biosynthesis of the GSL. Glycosyltransferases in the ER sequentially add sugars to produce the various glycolipids. Gangliosides (i.e., glycosphingolipids containing sialic acid) are produced by the addition of NANA to lactosyi-ceramide to form Gmi, which can then be further glycosylated to Gm2 and then Gms- Globosides also come from lactosyi-ceramide by addition of another Gal and then a GalNAc. Figure 5 Pathways of biosynthesis of the GSL. Glycosyltransferases in the ER sequentially add sugars to produce the various glycolipids. Gangliosides (i.e., glycosphingolipids containing sialic acid) are produced by the addition of NANA to lactosyi-ceramide to form Gmi, which can then be further glycosylated to Gm2 and then Gms- Globosides also come from lactosyi-ceramide by addition of another Gal and then a GalNAc.
Keenan, T. W., Morre, D. J., and Basu, S., 1974, Ganglioside biosynthesis. Concentration of glycosphingolipid glycosyltransferases in Golgi apparatus from rat liver, /. Biol Chem. 249 310. [Pg.491]

See other pages where Glycosyltransferases in Glycosphingolipid Biosynthesis is mentioned: [Pg.1446]    [Pg.1447]    [Pg.1449]    [Pg.1451]    [Pg.1453]    [Pg.1455]    [Pg.1457]    [Pg.1459]    [Pg.1461]    [Pg.1446]    [Pg.1447]    [Pg.1449]    [Pg.1451]    [Pg.1453]    [Pg.1455]    [Pg.1457]    [Pg.1459]    [Pg.1461]    [Pg.244]    [Pg.266]    [Pg.448]    [Pg.270]    [Pg.1765]    [Pg.2284]    [Pg.383]    [Pg.384]    [Pg.94]    [Pg.178]    [Pg.180]    [Pg.397]    [Pg.406]    [Pg.179]    [Pg.416]    [Pg.1446]    [Pg.1567]    [Pg.229]   


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