Glycosylation Methods in Carbohydrate Synthesis

Some General Considerations Concerning the Stereochemistry of Glycosylation Reactions 

Since the first glycosylation method was reported by Koenigs and Knorr (13) a 

Under certain conditions a glycosylation reaction can be highly stereoselective to give one glycosyl anomer. For example, it is relatively easy to achieve 

R = protecting group R OH = glycosyl acceptor Ac = acetyl X = leaving group 

Glycosylation Methods Using Glycosyl Halides as Donors 

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