Glycopeptide, relationship

Chemistry, structure-activity relationships, and prospects of semisynthetic glycopeptides (including cyclic ones) 97F313. 

Fig. 20. Schematic diagram of MRM assays and a typical procedure for MRM setting. (A) The general concept of MRM. (B) The MS/MS spectrum of PA-labeled sialyl glycopeptide from egg yolk. (C) The MRM chromatogram under different collision energies (CE) at 22, 27,32, 37, and 42 eV for 724.6/863.3 as Q1/Q3. (D) Relationship between fragment-ion counts versus CE for MRM assay [the numerical value means each coefficient of variation (CV)]. (E) Relationship between fragment-ion counts versus the amount of PA-labeled glycopeptide. This figure is adapted from ref. 113.

STRUCTURAL MODIFICATIONS OF GLYCOPEPTIDE ANTIBIOTICS AND STRUCTURE ACTIVITY RELATIONSHIP (SAR) STUDIES... 

Tlie increasing importance discovered for carbohydrate stmctures and their stracture-function relationships is necessitating improved techniques in synthesis and analysis of carbohydrates, glycoproteins, and glycopeptides. Progress toward tlie automated synthesis has been reported and provides compunds for biological and phaniiaceutical studies. 

Nagarajaii R. Structure-activity relationships of vancomycin-type glycopeptide antibiotics. J Antibiot 1993 46 1181-1195. 

MitcheU CR, Armstrong DW, Berthod A (2007) Could linear solvation energy relationships give insights into chiral recognition mechanisms 2-Characterization of macrocyclic glycopeptide stationary phases. J Chromatogr A 1166 70-78... 

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