Phosphoglycerate kinase, glycolysis

Glycolysis (phosphoglycerate kinase, pyruvate kinase two ATPs are expended) 2... 

Glycolysis Glyceraldehyde-3-phosphate dehydrogenase Phosphoglycerate kinase Pyruvate kinase... 

PEP is converted to fructose 1,6-bisphosphate in a series of steps that are a direct reversal of those in glycolysis (see Topic J3), using the enzymes enolase, phosphoglycerate mutase, phosphoglycerate kinase, glyceraldehyde 3-phosphate dehydrogenase, triose phosphate isomerase and aldolase (see Fig 1). This sequence of reactions uses one ATP and one NADH for each PEP molecule metabolized. 

Figure 2.5 Gluconeogenesis is the reversal of glycolysis, attained through the use of four unique enzymes glucose-6-phosphatase (A), fructose-1,6-bisphosphatase (5), PEP carboxykinase (6) and pyruvate carboxylase (7). Although phosphoglycerate kinase is shared with glycolysis, in gluconeogenesis this reaction requires the input of ATP.

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