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Glycogen phosphorylase glucose complex

Several simple deoxyfluoro sugars and glycosyl fluorides were utilized " as probes for hydrogen bonding in the glycogen phosphorylase-o-glucose complex. [Pg.222]

Glycogen phosphorylase (GP) is a dimeric enzyme that catalyzes the degradation of glycogen to glucose. Its structure in both the resting (GPb) (62) and activated (GPa) (26) forms has been solved in complex with allosteric effectors. [Pg.314]

Inhibitors of the enzyme glycogen phosphorylase have been studied for their ability to lower blood glucose levels.35 37 In order to study the nature of the binding of glucose derived substrates to glycogen phosphorylase, the product shown in Scheme 1.4.438 was complexed to the enzyme and studied via x-ray crystallography.39 Aside from demonstrating reasonable inhibitors, the... [Pg.12]

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See also in sourсe #XX -- [ Pg.30 ]



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Glucose glycogen

Glycogen phosphorylase

Glycogen phosphorylases

Phosphorylase

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