Glycogen phosphorylase conformational states

Glycogen phosphorylase conforms to the Monod-Wyman-Changeux model of allosteric transitions, with the active form of the enzyme designated the R state and the inactive form denoted as the T state (Figure 15.17). Thus, AMP promotes the conversion to the active R state, whereas ATP, glucose-6-P, and caffeine favor conversion to the inactive T state. 

Consider the diagram of the different conformational states of muscle glycogen phosphorylase in Figure 21.2. Answer the following questions. 

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