Glycine receptor cerebellum

The functional implications of the presence of glycine receptor subunits and gephyrin in the cerebellum are poorly understood. Granule cells express a3, the P subunit and gephyrin and, therefore, have all the ingredients to produce functional glycine receptors. 

The cerebellum, however, displays a significant number of pHjglycine binding sites mainly distributed over the granular layer (Bristow et ah, 1986), but these sites are assumed to represent the glycine coagonist sites of NMDA receptors (see Section 3.3.1.). 

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