Glycine lower alkyl ester

S,N-Ditrityl-L-cysteine diethylamine selt L-Tyrosine lower alkyl ester L-lsoleucine lower alkyl ester Benzyl-L-proline hydrochloride L-Leucine lower alkyl ester Ammonia Hydrogen chloride Glycine lower alkyl ester... 

Skeletal Biocompatibility. Two Substituent Groups Attached to the Same Phosphazene Skeleton. Hydrolytical Instability 0 II — NH- CH2— C- OC2H5 Glycine or Lower Alkyl Aminoacid Esters Hydrolytically Unstable Polymers. Bioerodible Materials. Drug Delivery Systems. Tissue Engineering... 

Dimeric Cinchona alkaloid ammonium salts have also been evaluated in LL-PTC alkylation of A -(diphenylmethylene)glycine tcrt-butyl ester (Scheme 15). meta-Dimer 18 generates a-alkyl derivative 11 in excellent yield and ees, whereas ortho and para dimers afford lower and scarce enantioselective alkylations, respectively [68],... 

The meto-dimeric catalyst 25a was found to be more efficient than the other two dimeric catalysts 24 and 26 in the asymmetric alkylation of N-(diphenylmethylene) glycine tert-butyl ester. Soon after, a trimer catalyst 27 was developed by the introduction of three cinchona units on the phenyl spacer, which showed enan-tioselectivity comparable to that with the dimeric catalyst 25a for the asymmetric alkylation even at a lower catalyst loading condition [57]. Further investigation led to the discovery of an efficient and practical 2,7-naphthalene-based dimeric... 

Takabe et al. [90] described a Cj-symmetric quaternary ammonium salt 57 and applied it to the asymmetric benzylation of N-(diphenyhnethylene) glycine tert-butyl ester. A much lower enantioselectivity was obtained by using the mono- or di-OH group-containing phase-transfer catalyst instead of (R,R,R)-57, which clearly illustrated the importance of a second coordination site to achieve reasonable selectivities. Starting from readily accessible a-amino acids, Ooi and coworkers recently designed and prepared a series of chiral 1,2,3-triazolium 58, and their potential as phase-transfer catalysts was demonstrated through application to the asymmetric alkylation of 3-substituted oxindoles [91]. 

The rearrangement products derived from aromatic and non-aromatic heterocyclic amines crystallize readily from the lower alcohols. Unlike those of many of the A-substituted glycosylamines, the crystals are not solvated. On the other hand, the ketose derivatives of aralkyl- and alkyl-amines, such as 2-phenylethylamine, ethanolamine, diethanolamine, glycine ethyl ester, and phenylalanine (see Table II), are hydrated or alcoholated, or both, and are difficult to isolate in pure crystalline form. The crystals which have been isolated were hygroscopic. Alcohols, aqueous alcohols, and water are the most commonly used solvents for crystallization. Acetone, ether, or benzene have been added to the alcoholic media in order to increase the yield of crystalline compound. The use of solvents that contain peroxides promotes decomposition of the crystals during storage. ... 

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