Glycid ester condensations

Benzilic acid rearrangement Benzoin reaction (condensation) Blanc chloromethylation reaction Bouveault-Blanc reduction Bucherer hydantoin synthesis Bucherer reaction Cannizzaro reaction Claisen aldoi condensation Claisen condensation Claisen-Schmidt reaction. Clemmensen reduction Darzens glycidic ester condensation Diazoamino-aminoazo rearrangement Dieckmann reaction Diels-Alder reaction Doebner reaction Erlenmeyer azlactone synthesis Fischer indole synthesis Fischer-Speior esterification Friedel-Crafts reaction... 

Darzens glycidic ester condensation generally involves the condensation of an aldehyde or ketone 2 with the enolate of an a-halo ester 1 which leads to an a,P-epoxy ester (a glycidic ester) (3). Thus the reaction adds two carbons to the electrophile however, the reaction has been primarily developed as a one-carbon homologation method. That is, subsequent to the condensation, the ester is saponified and decarboxylation ensues to give the corresponding aldehyde or ketone 5.2... 

Glycerol-cr,y-dichlorohydrin, 31, 2 Glycidic ester condensation, 34, 54 Glycine, 33, 1... 

Rosen, T. Darzens Glycidic Ester Condensation In Comprehensive Organic Synthesis Trost, B. M. Fleming, I., Eds. Pergamon Oxford, 1991, vol. 2, pp 409-439. (Review). 

Myers, B. J. Darzens Glycidic Ester Condensation In Name Reactions in Heterocyclic Chemistry, Li, J. J. Corey, E. J., Eds. Wiley Sons Hoboken, NJ, 2005, 15—21. (Review). 

Darzens Condensation (Darzens-Claisen Reaction, Darzens Glycidic Ester Condensation)... 

Dalton s law of partial pressures, 12 Darzens glycidic ester condensation, 906J, 907... 

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