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Glycero-3-phosphorylcholine

Dimyristoyl- and dipalmitoyllecithin were synthesized by acylation of sn-glycero-3-phosphorylcholine with fatty acid anhydrides as described by Cubero Robles and van den Berg (23). The sn-glycero-3-phosphoryl-choline was prepared by deacylation of egg-yolk lecithin according to... [Pg.135]

Figure I The pH-dependence of the acyl migration of lysophospholipids is shown. The log of the pseudo first-order rate constant it if or the rearrangement of 2-palmitoyl- n-glveero-3-phosphorYlchotine into l-palmitoyl-sn-glycero-3-phosphorylcholine is plotted against the pH buffered with 50mM iris HCl ( ). 50m M citrate (O), or 0.1 M HCI and 160m M Triton X-100 (A) to solubilize the reaction products at acidic pH. Figure I The pH-dependence of the acyl migration of lysophospholipids is shown. The log of the pseudo first-order rate constant it if or the rearrangement of 2-palmitoyl- n-glveero-3-phosphorYlchotine into l-palmitoyl-sn-glycero-3-phosphorylcholine is plotted against the pH buffered with 50mM iris HCl ( ). 50m M citrate (O), or 0.1 M HCI and 160m M Triton X-100 (A) to solubilize the reaction products at acidic pH.
PAF, platelet activating factor, l-0-alkyl-2-acetyl-5tt-glycero-3-phosphorylcholine... [Pg.844]

PAF is an ether linked pho hoglyceiide. Giemical stmctuie of this lipid mediator was determined to be l-O-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine (Fig. 1). In literature PAF has also been termed as PAF-acether, and AGEPC (alkyl acetyl glycero ether phosphoryl Moline). Excellent reviews have documented these historical developments (Hanahan, 1986, Snyder, 1985). In this... [Pg.121]

Alkyl-2-acyl-sn-glycero-3-phosphorylcholine (phosphatidalcholine, a plasmalogen)... [Pg.405]

Li, L., X.P. Wang, and K. Wu The therapeutic effect of oxidized l-palmitoyl-2-arachido-noyl-sn-glycero-3-phosphorylcholine in rodents with acute necrotizing pancreatitis and its mechanism. Pancreas 35 (2007) e27-e36. [Pg.347]

Walton, K.A. et al. Receptors involved in the oxidized l-pahnitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine-mediated synthesis of interleukin-8. A role for Toll-like receptor 4 and a glycosylphosphatidyhnositol-anchored protein. J. Biol Chem. 278 (2003b) 29661-6. [Pg.350]

Rouhanizadeh, M., Hwang, J., Clempus, R. E., Marcu, L., Lassegue, B., Sevanian, A., and Hsiai, T. K. 2005. Oxidized-l-pahnitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine induces vascular endothelial superoxide production Implication of NADPH oxidase. [Pg.20]

PEIPC l-palmitoyl-2-(5,6-epoxyisoprostaneE2)-i -glycero-3-phosphorylcholine PGPC l-palmitoyl-2-glutaroyl-OT-glycero-3-phosphocholine... [Pg.225]

Stachyurin, in C-10036 l-Stearoyl-2-arachidonoyl-5 -glycero-3-phosphorylcholine, see 0-10010 Stearoylarachidonylphosphatidylcholine, in 0-10010... [Pg.499]

Several relevant experimental and instrumental details are outlined next. The synthetic PC used (13) were PC(SA c9,tl 1-CLA), l-stearoyl-2-transl0,dsl2-octadecadienoyl-r -glycero-3-phosphorylcholine [PC(SA flO,cl2-CLA)] and [PC(SA LA)], that were custom synthesized by Matreya, Inc. (Pleasant Gap, PA). [Pg.140]

Freund s adjuvant (1.4-140 ( 1/25x10 peritoneal exudate cells of mice) induced a significant activation of phosphohpase A (EC 3.1.1.4) (Munder et al. 1973). The relative concentrations of lysolecithin (1 -acyl-s -glycero-3-phosphorylcholine), neutral... [Pg.383]


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