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Glutamate and its analogs

Fig. 2.1 Structures of glutamate and its analogs. L-Glutamate (a) NMDA, N-methyl-D-aspartate (b) kainate (c) ibotenate (d) AMPA (e) domoate (f) L-AP4 (g) BMAA (h) and quisqualate (i)... Fig. 2.1 Structures of glutamate and its analogs. L-Glutamate (a) NMDA, N-methyl-D-aspartate (b) kainate (c) ibotenate (d) AMPA (e) domoate (f) L-AP4 (g) BMAA (h) and quisqualate (i)...
The mechanisms underlying glutamate and its analog-induced neuronal damage are quite complex. The molecular sequence of these events is not fully understood. The mechanisms include inhibition of mitochondrial function and increases... [Pg.33]

Farooqui, A. A., Anderson, D. K., and Horrocks, L. A. (1994). Potentiation of diacylglycerol and monoacylglycerol lipase activities by glutamate and its analogs. J. Neurochem. 62, S74B... [Pg.69]

Table 6.2 Alterations in enzymic activities of brain tissue induced by glutamate and its analogs... Table 6.2 Alterations in enzymic activities of brain tissue induced by glutamate and its analogs...
Table 8.2 Involvement of glutamate and its analogs in neurological and neuropsychiatric disorders... Table 8.2 Involvement of glutamate and its analogs in neurological and neuropsychiatric disorders...
The treatment of neuronal cultures with glutamate and its analogs results in a dose-dependent increase in CPLA2, COX, and LOX activities and arachidonic acid, eicosanoids and ROS release (Dumuis et al., 1988 Lazarewicz et al., 1990 Farooqui et al., 2003b Adams et al., 1996 Manev et al., 1998). Glutamate recep-... [Pg.209]

The range of polymers which were found to be able to form liquid crystalhne systems has been considerably extended. Poly(Y-benzyl-L-glutamate) and its analogs, as well as para-aromatic polyamides, exhibit this property in solutions, which served the basis for relating them to lyotropic liquid crystals (see Sect. 2.1). Subsequently, the classes of polymers were found which exhibited such a transition during a change of temperature thermotropic liquid crystals). [Pg.76]

Farooqui AA, Anderson DK, Horrocks LA (1993) Effect of glutamate and its analogs on diacylglycerol and monoacylglycerol lipase activities of neuron-enriched cultures. Brain Res 604 180-184... [Pg.203]

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And glutamate

Glutamate analogs

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