Glucose Strips

J. Risley,/. Chem. Educ. 68,1054 (1991). Preparing Solutions in the Biochemistry Lab. J. Wang and C. Macca,/. Chem. Educ. 73, 797 (1996). Use of Blood-Glucose Strips for Introducing Enzyme Electrodes and Modern Biosensors. ... 

For some cell lines, the glucose concentration needs to be monitored, since glucose starvation can occur The use of blood glucose strips is very effective. A drop of spent medium after a reservoir has been changed or a drop of harvested supernatant is placed on the reaction site of the strip, and left for 1 mm This is wiped off, and after a further minute, the color change is compared with a reference chart... 

Precision Measuring the precision of blood glucose strips is very easy and involves testing a number of strips with the same sample with a fixed glucose level. The standard deviation and relative standard deviation (also called percent coefficient of variation) can then be easily calculated for the strips. There is no such easy precision measurement for CGM devices. The manufacturers have placed two CGM devices in a person and then compared the glucose readings made by each... 

The calibration is done with one or more blood glucose measurements using blood glucose strips. The blood measurement will then set the glucose sensitivity... 

Figure 12-7 Schematic diagram of the reactions taking place in a MediSense electrochemical glucose strip. (Modified from Henning TP, Cunningham TP. Biosensors for personal diabetes management In Ramsay G ed. Commercial Biosensors. New York John Wiley Sons, 1998 3-46.)...

One of the attractive features of the thick film process is that the capital investment for thick film printing is relatively low. Basically, it involves a thick film printer, an oven, and a furnace. One of the notable commercial successes of using thick film techniques is the manufacture of glucose strips for diabetic patient management. The strip involves thick film printing and is cost-effective, making the disposable strip a reality. 

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