Glucose oxidase, nitrospiropyran-modifie

Figure 12.4 Photoinduced bioelectrocatalyzed oxidation of glucose to gluconic acid by glucose oxidase (COD) reconstituted with a nitrospiropyran-modified FAD cofactor (Sp-FAD) assembled as a monolayer on the Au electrode. Fhe Sp-FAD reveals reversible photoisomeriz-able properties yielding nitromerocyanine-FAD isomer (MRH+-FAD) [34]...

Willner, I., Blonder R., Kate, E., Stocker A., and Buckmann, A. F. Reconstitution of apo-glucose oxidase with a nitrospiropyran-modified FAD cofactor yields a photoswitchable biocatalyst for amperometric transduction of recorded optical signals. J. Am. Chem. Soc. 

Photostimulation of redox enzymes could transduce recorded optical signals as an amperometric response by their electrical interaction with electrode interfaces. For example, amperometric transduction of recorded optical signals was accomphshed using nitrospiropyran-modified glucose oxidase as photoswitchable material (Fig. 44) [14]. 

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