Glucose Homeostasis in Biotin Deficiency

2 Fatty Liver and Kidney Syndrome in Biotin-Deficient Chicks 

Birds are especially sensitive to biotin deficiency, at least partly because their intestinal flora make little or no contribution to biotin intake. This is of considerable commercial importance with intensively reared poultry. In adult birds, biotin deficiency does not affect egg production, but does reduce the amount of biotin in the eggs, thus impairing embryonic development. In severe deficiency, the hatchability of the eggs can fall to near zero. 

The problem is thus obviously not simply one of biotin deficiency, although supplementary biotin will alleviate the condition. 

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