Glucose cell transport, glycolysis

The first segment of glucose catabolism is called glycolysis. This process begins when glucose is transported into a cell. In a series of reactions within the cell, each of which requires a specific enzyme, a single six-carbon glucose molecule is converted to... 

Glucose must be transported into the cell for glycolysis to occur. There are specific glucose transporters in most cells some are insulin stimulated and others are refractory to insulin. 

J. Chen, and J. Russo, Dysregulation of glucose transport, glycolysis, TCA cycle and glutaminolysis by oncogenes and tumor suppressors in eaneer cells. Biochim. Biophys. Acta., 1826 (2012)370-84. 

Glycolysis is a process that takes place in all cells of the body. It is important in which lack mitochondria and use glycolysis as their only source of energy. Entry of one molecule of glucose into the glycolysis pathway leads to the production of. ... .. molecules of NADH, which undergo. by the electron transport chain in the production of ATP. Glucose enters cells by... 

The transport system that conveys malate and a-ketoglu-tarate across the inner mitochondrial membrane (see Fig. 19-27) is inhibited by n-butylmalonate. Suppose n-butyl-malonate is added to an aerobic suspension of kidney cells using glucose exclusively as fuel. Predict the effect of this inhibitor on (a) glycolysis, (b) oxygen consumption, (c) lactate formation, and (d) ATP synthesis. 

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