Glucosamine synthesis

M.D. Roos, I.O. Han, A.J. Paterson and J.E. Kudlow, Am. J. Physiol Cell Physiol, 1996, 270, C803-C811, Role of glucosamine synthesis in the stimulation of TGF-a gene transcription by glucose and EGF. 

Chitosan freeze-dried fleeces support chondrocyte attachment and synthesis of extracellular matrix [344]. Chitosan was used to assist the spontaneous tissue repair of the meniscus [345]. The repair of the cartilage and the prevention of its degradation in osteoarthritis is, however, possible with the association of glucosamine sulfate salt and chondroitine sulfate, the latter being particularly effective [346]. 

Enhanced availability of exogenous glucosamine is beneficial for the synthesis of hyaluronan because endogenous glucosamine is insufficient to achieve the high concentration of UDP-N-acetyl glucosamine necessary to... 

Synthesis of /J-u-Galactosides of Y-Acetyl-D-Glucosamine by Various Mammalian Tissues. J. biol. Chemistry 220, 71 (1956). 

Cifonelli The Biosynthesis of Hyaluronic Acid by Group A Streptococcus. IV. Role of Glucosone as an Intermediate in the Synthesis of Glucosamine. J. biol. Chemistry 216, 549 (1955)-... 

Haley, F., and H. A. Lardy Phosphoric Esters of Biological Importance. VI. The Synthesis of D-Glucosamine 6-Phosphate and N-Acetyl-D-glucos-amine 6-Phosphate. J. Amer. chem. Soc. 78, 1393 (1956). 

Fig. 8. First synthesis of carbohydrate-substituted polymers by ROMP using a defined orga-nometallic initiator. Grubbs synthesis of glucosamine-substituted polymers...

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