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Pentaacetyl gluconic acid

Gluconic acid, pentaacetyl-,D-, and Gluconyl chloride, pentaacetyl-, D-)... [Pg.104]

The aldehydo acetates have been oxidized to the corresponding aldonic acids without deacetylation by the action of bromine in the presence of potassium bicarbonate. In this manner. Major and Cook obtained pentaacetyl-D-gluconic acid. A modification of this method was used by Wolfrom, Brown and Evans for the preparation of pentaacetyl-D-galactonic acid. [Pg.153]

By an analogy to the radical syntheses above, the carbon chain elongation reaction was achieved by Barton et al. [109] in the reaction with ethyl a-trifluoroacetoxy acrylate 165. Under radical conditions 165 was coupled with the ester 164 prepared from pentaacetyl gluconic acid and /V-hydroxy-2-thiopiridone (Scheme 35) to afford an unstable intermediate 166, readily convertible to the unsaturated a,p-keto acid 167. The methoxymercuration-demercuration of 167 gave a low selectivity, providing the mixture of 3-deoxy-4-methoxy-D-man/jo and D-g/wco-octulosonic acids (4 3) in a moderate yield [110]. [Pg.451]

The cyclization of pentaacetyl-o-gluconic thioamide with chloroacetone and of pentaacetyl-D-galactonic acid thioamide with phenacyl bromide give the corresponding 4-substituted 2-(D-galactopentaacetoxypentyl)-thiazoles (27) (660) but in low yield (23 to 27%) (Scheme 13). The products may be deacetylated in the usual way. These compounds are interesting from a pharmacological point of view. [Pg.188]


See other pages where Pentaacetyl gluconic acid is mentioned: [Pg.114]    [Pg.60]    [Pg.57]    [Pg.355]    [Pg.58]    [Pg.114]    [Pg.60]    [Pg.57]    [Pg.355]    [Pg.58]   
See also in sourсe #XX -- [ Pg.41 , Pg.79 ]

See also in sourсe #XX -- [ Pg.41 , Pg.79 ]

See also in sourсe #XX -- [ Pg.41 , Pg.79 ]




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