0-Glucoheptose

Stacey started research in an inspiring and stimulating atmosphere that he strove to maintain, add to, and develop when it became his turn to lead the department. His earliest research was with Haworth and his key partner E. L. Hirst [Adv. Carbohydr. Chem. Biochem., 35 (1978) 1 -29] on aspects of the chemistry of glucoheptose. His first publication with them in 1931 was entitled Walden Inversion in the a-Glucoheptose Series, followed in the next year by a report on the methylation of monocarboxylic acids derived from aldoses and the structure of pentamethyl a-gluco-heptonolactone. He found this to be a difficult project because, initially, he could not crystallize his stock of glucoheptose. Then, as later, he found crystallization to be a challenging problem. 

D-Glucoheptosone was prepared by treating D-glucoheptose phenylos-azone with concentrated hydrochloric acid.196 The osone was employed for the synthesis of D-glucoheptoascorbic acid. 

C7H1407 D-gZt/cero-/3-D-guZo-Heptopyranose (/3-D- glucoheptose ) (BDGHEP)52... 

On nitration it produces an expl compd d-a-GIucoheptose Hexanitrate, O3NQ.CH3(CH.ONQ2)s.CH0 mw 480.18 N 17.50%, OB to COa +3-33% colorless ndls (from ale) mp 100° reduces Fehling s soln on warning. Can be prepd by nitrating d-o-Glucoheptose (Refs 2, 3 4). It is a powerful expl... 

D-glucose, D-maltose, D-glucoheptose, 3-O-methyl-D-glucose D-glucose, D-maltose, D-glucoheptose, 3-O-methyl-D-glucose... 

On nitration it produces an expl compd d-a-Glucoheptose Hexonitrote,... 

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