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Glucocerebrosidase human placental

A. General description Alglucerase is a monomeric glycoprotein, with a molecular weight of 59.3 kDa, consisting of 497 amino-acid residues. It is a modified form of P-glucocerebrosidase from pooled human placental tissue. Alglucerase differs from... [Pg.256]

Alglucerase is a modified form of human /S-glucocerebrosidase. Ceredase is a citrate buffered solution of alglucerase manufactured from human placental tissue. It has largely been replaced by Cerezyme, which is produced by recombinant DNA technology. Both are given intravenously in the treatment of type I Gaucher s disease. [Pg.159]

Figure 1 Carbohydrate composition of the predominant oligosaccharide chain of human placental glucocerebrosidase. Gal = Galactose GlcNAc = N-acetylglucosamine Man = mannose NeuNac = N-acetylneuraminic acid. Figure 1 Carbohydrate composition of the predominant oligosaccharide chain of human placental glucocerebrosidase. Gal = Galactose GlcNAc = N-acetylglucosamine Man = mannose NeuNac = N-acetylneuraminic acid.
S. Takasaki, G. J. Murray, F. S. Furbish, R. O. Brady, J. A. Barranger, and A. Kobata. Structure of the N-asparagine-like oligosaccharide units of human placental p-glucocerebrosidase. J. Biol. Chem. 259 10112 (1984). [Pg.280]

See other pages where Glucocerebrosidase human placental is mentioned: [Pg.279]    [Pg.486]    [Pg.526]    [Pg.262]    [Pg.264]    [Pg.280]    [Pg.281]    [Pg.197]    [Pg.229]    [Pg.179]    [Pg.256]    [Pg.178]   
See also in sourсe #XX -- [ Pg.264 , Pg.265 ]

See also in sourсe #XX -- [ Pg.264 , Pg.265 ]



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