Glucan polymers, microbial

It is noteworthy that most of the chemical shift values for all three polymers may be closely approximated ( ) by calculations based on data for monomeric reference compounds. These findings illustrate, therefore, the general validity of studies on low molecular weight model compounds for einalysis of spectra of carbohydrate polymers. Many examples of equally satisfactory comparisons of this kind are to be found in studies on other polysaccharides (11,23). These polymers include glucans (l6), mannans (2k, 2 ), limit dextrins (26), lichenin (2j), agarose (28) and various polysaccharides of fungal and microbial orgins (e.g., 7,8,29-31). Observed departures from expectation have been attributed to specific conformational influences ( 8). 

The LAL reaction is specific for endotoxin with the exception of a glucose polymer from cellulose, yeast, and certain other microbial sources, known as (1 —> 3)-p-D-glucanJ This glucan activates LAL the same as endotoxin and produces a synergistic enhancement of the PPC in kinetic LAL studies. The BET allows glucan-containing products to be tested by LAL reagents that are treated to make them specific for endotoxin and avoid a false-positive result. 

Microbial 3-Glucan Hydrolases and Lysis of Plant Cell Wall Polymers. Many soil and aerial pathogens gain access to host tissues by enzymic lysis of epidermal cell walls of roots, leaves, stems, etc.. Phytopathogenic organisms possess an array of inducible polysaccharide hydrolases capable of degrading the complex polysaccharides of the plant cell wall (, 10). The... 

Kambourova M, Mandeva R, Dimova D, Poli A, Nicolaus B, Tommonaro G. Production and characterization of a microbial glucan, synthesized by Geobacillus tepidamans V264 isolated from Bulgarian hot spring. Carhohydr Polym 2009 77 338-43. 

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