Glomus cells destruction

Verna, A., Rowny, M., and Leitner, L.M., Loss of chemoreceptor properties of the rabbit carotid body after destruction of the glomus cells. Brain Res., 100, 13-23, 1975. 

To solve the problem presented above, two convergent strategies have been followed (1) to demonshate whether chemosensory nerve endings can sense physiological chemical stimuli when separated from glomus cells, and (2) to find out if chemoreception fails after destruction of glomus cells. 

V. Does Chemoreception Fail After Destruction of Glomus Cells ... 

Local destruction of glomus cells is commonly accompanied by elimination—or at least dedifferentiation—of sustentacular cells, whose actions have seldom been searched for and whose importance is poorly understood. 

Destruction of the parenchymal cells of the carotid body (both glomus and sustentacular cells)—by either cryocoagulation or by hgature-induced ischemia— is accompanied by a profound distortion of the rich vascularization of the carotid body, whose consequences may contribute to the abohtion of the hypoxic chemoreception observed. 

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