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Glomerular filtration rate drug transport

Age In newborn infants, the glomerular filtration rate and tubular transport is immature, which takes 5 to 7 months to mature. Also, the hepatic drug metabolism capacity is also inadequate (that is why chloramphenicol can produce grey baby syndrome ), and due to the higher permeability of blood brain barrier, certain drugs attain high concentration in the CNS. [Pg.40]


See other pages where Glomerular filtration rate drug transport is mentioned: [Pg.265]    [Pg.67]    [Pg.199]    [Pg.9]    [Pg.161]    [Pg.22]    [Pg.127]    [Pg.551]    [Pg.7]    [Pg.511]    [Pg.113]    [Pg.248]    [Pg.340]    [Pg.6]    [Pg.152]    [Pg.238]    [Pg.736]    [Pg.50]    [Pg.41]    [Pg.26]    [Pg.41]    [Pg.208]    [Pg.217]    [Pg.339]   
See also in sourсe #XX -- [ Pg.46 ]




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