Globin developmental regulation

Karlsson, S., and A. W. Nienhius, Developmental regulation of human globin genes. Ann. Rev. Biochem. 54 1071-1108, 1985. 

Each gene in the (3-globin locus has individual regulatory elements—a promoter, silencers, or enhancers that control its developmental regulation. The promoters controlling the y and (3-globin genes have been intensively studied because of their clinical relevance. 

Knezetic J. A. Felsenfeld, G. (1993). Mechantem of developmental regulation of an, the emixyonic a globin gene. Mol Cell Biol, 13, 4632-9. 

Minie, M., Clark, D., Trainor, C. ei al (1992a). Developmental regulation of globin gene expression./. CellSci. 16s, 15-20. 

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